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       HEREDITY HEALTHCARE AND LIFE SCIENCES     Contact us: For healthcare: 7381298980 For lifesciences:+ 919938568088 Website:www.heredity.in Email: support@hdls.in     Written by: Sweta Yadav       Introduction: In this rapid outburst of Covid-19 virus the statistical analysis of the data found from various survey leads to the conclusion that there is a need for quick and sensitive diagnostic measure in order to assess the spread of this novel virus and further defining controllable protocols. Currently, quantitative real-time polymerase chain reaction (qRT-PCR) is being used widely to detect COVID-19 from wide range of biological specimens, which is tedious, labor dependent and not so easy to execute in remote and resource limited areas. This might act as barrier in acquiring realistic data of infectivity and community spread of SARS-CoV-2 in the population. This review focuses the advantages of Bio

         HEREDITY HEALTHCARE AND LIFESCIENCES Contact us : For healthcare: 7381298980 For life sciences :+919938568088 Email: support@hdls.in Website:www.heredity.in Written by :                           SAPTARSHI BHATTACHARYYA Golgi ribbon can undergo distinct disassembly processes that reflect the cellular state or environmental demands and stress . It can also be detached and positioned at specific cellular locations to gain additional functionalities during differentiation, or fragmented to different degrees along disease progression or upon cell death . In this article, unknown areas in this realm has been pointed out so that these can open the path for new disruptive innovations.   1) The reason why the Golgi ribbon is disassembled in animal mitosis is still shrouded. 2) T he extent of interdependency and redundancy of the multi-step mitotic golgi disassembly mechanism demands further investigation. 3) T he precise surveillance cascade that halts mitotic entry nee

            HEREDITY HEALTHCARE AND  LIFE SCIENCES Contact us : For healthcare: 7381298980 For lifesciences :+919938568088 Email: support@hdls.in Website:www.heredity.in Written by : SAPTARSHI BHATTACHARYYA   l   INTRODUCTION   COVID-19 infection in pregnan t women may result in rapid health deterioration , including the f o etus. O n the basis of the recommendations from National Technical Advisory Group on Immunization (NTAGI), a pregnant woman will have the choice to take the vaccination after she is given detailed information regarding the associated risks . COVID-19 positive pregnant women are more likely to require intensive care as compared to their non-pregnant counterparts. With respect to the current situation of the SARS-CoV-2 pandemic, experts have suggested that the COVID-19 vaccine may be offered to pregnant women if no contraindications exist. The motive is to weigh risk versus benefit on an individualized basis, s uch that a pregnant woman can m

HEREDITY HEALTHCARE AND  LIFE SCIENCES Connect us : 7381298980 9 / 938568088 Email: support@hdls.in www.heredity.in written by :  Saptarshi Bhattacharyya. SARS-CoV-2, characterized by its high rates of mutation is a potential threat to humanity. Many investigations have been conducted on the virus’ mutational profiles, but its effects on the human reproductive system is yet to be adequately elucidated. In this paper, a detailed explanation has been made on how ACE2 is related to the human reproductive system (both male and female) and COVID-19 infection. SARS-CoV-2 invades the host cell by binding to the ACE2 (Angiotensin converting enzyme) receptor. ACE2 is a key component of Renin-angiotensin system (RAS), which modulates the cleavage of angiotensin II (AngII) and angiotensin(1-7) to exert its physiological mechanisms and functions. Upon cell invasion, COVID-19 disrupts the RAS system and downregulates ACE2 expression. Thus, concentration of AngII increases, resulting in increased pr

  Fertility Markers/ Prenatal Diagnostics by PCR & Sequencing 1 Mutation analysis for Beta Thalassemia (5 common Mutations) ARMS PCR Mutation analysis for Beta Thalassemia (7 common Mutations) ARMS PCR Mutation analysis for Beta Thalassemia (20 Common Mutations) ARMS PCR   HbE (Hemoglobin E) Mutation Screening ARMS PCR   Prenatal diagnosis for Beta Thalassemia (Known mutation) ARMS PCR 2 Prenatal diagnosis for Sickle Cell Anaemia (Known mutation) MLPA   Prenatal diagnosis for HbE (Hemoglobin E) (Known mutation) ARMS PCR 2 Mutation analysis for Sickle cell anemia ARMS PCR   FAMILY SCREENING FOR BETA THALASSEMIA 7 Common Mutation Panel (PROBAND, FATHER, INDEX CHILD & FETUS) MLPA   Al